best pistol \.45

What is the best round of a 45 cal pistol?
I just purchased a new Smith and Wesson 45 Special Chiefs. I will use it for home defense and wants to know what is the best ammunition for this weapon in particular would be. Thanks
I use Cor-Bon 185 gr + P rounds. Depending on the house, however, it is possible want to consider some of the rounds as Glasers rupture or MAG-SAFE. They will stop any intruders, but does not penetrate most of the drywall so that your baby is safe in the room next door! Edit: While I have not seen this particular one hand, S & W revolvers have been doing 45 ACP since 1917. I have had several, model 1917 (made by World War), the model of 25.2 in 4-in, and a stainless steel model 1989. All use of the famous "moon clips" to hold the rounds and facilitate removal of empty containers.
The best Pistols in the World III